Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia

BACKGROUND: Activated microglia elicits a robust amount of pro-inflammatory cytokines, which are implicated in the pathogenesis of tuberculosis in the central nervous system (CNS). However, little is known about the intracellular signaling mechanisms governing these inflammatory responses in microgl...

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Bibliographische Detailangaben
Hauptverfasser: Yang, Chul-Su, Lee, Hye-Mi, Lee, Ji-Yeon, Kim, Jeong-Ah, Lee, Sung Joong, Shin, Dong-Min, Lee, Young-Ho, Lee, Dong-Seok, El-Benna, Jamel, Jo, Eun-Kyeong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2235845/
https://ncbi.nlm.nih.gov/pubmed/18036262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-4-27
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