BIOSYNTHESIS OF INSULIN IN BOVINE FETAL PANCREATIC SLICES: THE INCORPORATION OF TRITIATED LEUCINE INTO A SINGLE-CHAIN PROINSULIN, A DOUBLE-CHAIN INTERMEDIATE, AND INSULIN IN SUBCELLULAR FRACTIONS

This communication reports the biosynthesis of insulin in the bovine fetal pancreatic slices in vitro. Double-chain proinsulin and insulin were found as major components in the mitochondrial-granule fraction of bovine fetal pancreas. Tritiated leucine was incorporated into a single-chain proinsulin,...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Tung, A. K., Yip, C. C.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1969
Onderwerpen:	Biological Sciences: Biochemistry
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC223584/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5257135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.63.2.442
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