BIOSYNTHESIS OF INSULIN IN BOVINE FETAL PANCREATIC SLICES: THE INCORPORATION OF TRITIATED LEUCINE INTO A SINGLE-CHAIN PROINSULIN, A DOUBLE-CHAIN INTERMEDIATE, AND INSULIN IN SUBCELLULAR FRACTIONS
This communication reports the biosynthesis of insulin in the bovine fetal pancreatic slices in vitro. Double-chain proinsulin and insulin were found as major components in the mitochondrial-granule fraction of bovine fetal pancreas. Tritiated leucine was incorporated into a single-chain proinsulin,...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1969
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC223584/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5257135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.63.2.442 |
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