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Inhibition of adhesive interaction between multiple myeloma and bone marrow stromal cells by PPARγ cross talk with NF-κB and C/EBPβ

Binding of multiple myeloma (MM) cells to bone marrow stromal cells (BMSCs) triggers expression of adhesive molecules and secretion of interleukin-6 (IL-6), promoting MM cell growth, survival, drug resistance, and migration, which highlights the possibility of developing and validating novel anti-MM...

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Autori principali: Wang, Li Hua, Yang, Xiao Yi, Zhang, Xiaohu, Farrar, William L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234797/
https://ncbi.nlm.nih.gov/pubmed/17785586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-038026
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