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Bone marrow stromal cells from multiple myeloma patients uniquely induce bortezomib resistant NF-κB activity in myeloma cells

BACKGROUND: Components of the microenvironment such as bone marrow stromal cells (BMSCs) are well known to support multiple myeloma (MM) disease progression and resistance to chemotherapy including the proteasome inhibitor bortezomib. However, functional distinctions between BMSCs in MM patients and...

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Bibliographic Details
Main Authors: Markovina, Stephanie, Callander, Natalie S, O'Connor, Shelby L, Xu, Guangwu, Shi, Yufang, Leith, Catherine P, Kim, KyungMann, Trivedi, Parul, Kim, Jaehyup, Hematti, Peiman, Miyamoto, Shigeki
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095250/
https://ncbi.nlm.nih.gov/pubmed/20604947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-176
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