Bone marrow stromal cells from multiple myeloma patients uniquely induce bortezomib resistant NF-κB activity in myeloma cells

BACKGROUND: Components of the microenvironment such as bone marrow stromal cells (BMSCs) are well known to support multiple myeloma (MM) disease progression and resistance to chemotherapy including the proteasome inhibitor bortezomib. However, functional distinctions between BMSCs in MM patients and...

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Detalhes bibliográficos
Main Authors: Markovina, Stephanie, Callander, Natalie S, O'Connor, Shelby L, Xu, Guangwu, Shi, Yufang, Leith, Catherine P, Kim, KyungMann, Trivedi, Parul, Kim, Jaehyup, Hematti, Peiman, Miyamoto, Shigeki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095250/
https://ncbi.nlm.nih.gov/pubmed/20604947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-176
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