Bone marrow stromal cells from multiple myeloma patients uniquely induce bortezomib resistant NF-κB activity in myeloma cells

BACKGROUND: Components of the microenvironment such as bone marrow stromal cells (BMSCs) are well known to support multiple myeloma (MM) disease progression and resistance to chemotherapy including the proteasome inhibitor bortezomib. However, functional distinctions between BMSCs in MM patients and...

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Autori principali: Markovina, Stephanie, Callander, Natalie S, O'Connor, Shelby L, Xu, Guangwu, Shi, Yufang, Leith, Catherine P, Kim, KyungMann, Trivedi, Parul, Kim, Jaehyup, Hematti, Peiman, Miyamoto, Shigeki
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095250/
https://ncbi.nlm.nih.gov/pubmed/20604947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-176
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