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Uncoupling of transfer of the presequence and unfolding of the mature domain in precursor translocation across the mitochondrial outer membrane

Translocation of mitochondrial precursor proteins across the mitochondrial outer membrane is facilitated by the translocase of the outer membrane (TOM) complex. By using site-specific photocrosslinking, we have mapped interactions between TOM proteins and a mitochondrial precursor protein arrested a...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Kanamori, Takashi, Nishikawa, Shuh-ichi, Nakai, Masato, Shin, Injae, Schultz, Peter G., Endo, Toshiya
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10097089/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.7.3634
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