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Uncoupling of transfer of the presequence and unfolding of the mature domain in precursor translocation across the mitochondrial outer membrane

Translocation of mitochondrial precursor proteins across the mitochondrial outer membrane is facilitated by the translocase of the outer membrane (TOM) complex. By using site-specific photocrosslinking, we have mapped interactions between TOM proteins and a mitochondrial precursor protein arrested a...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kanamori, Takashi, Nishikawa, Shuh-ichi, Nakai, Masato, Shin, Injae, Schultz, Peter G., Endo, Toshiya
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10097089/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.7.3634
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