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Two domains of Tim50 coordinate translocation of proteins across the two mitochondrial membranes

Biochemical and genetic experiments identify distinct roles of the two domains of Tim50 in the intermembrane space during translocation of proteins into the mitochondria via the TOM and TIM23 complexes. Hundreds of mitochondrial proteins with N-terminal presequences are translocated across the outer...

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Autori principali: Marcel G Genge, Shalini Roy Chowdhury, Vít Dohnálek, Kaori Yunoki, Takashi Hirashima, Toshiya Endo, Pavel Doležal, Dejana Mokranjac
Natura: Artigo
Lingua:Inglês
Pubblicazione: Life Science Alliance LLC 2023-12-01
Serie:Life Science Alliance
Accesso online:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202302122
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