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The Defensive Action of LYRM03 on LPS-Induced Acute Lung Injury by NF-κB/TLR4/NLRP3 Signals

The aim of the current investigation was to study the role of 3-amino-2-hydroxy-4-phenyl-valyl-isoleucine (LYRM03) in lipopolysaccharide (LPS)-induced acute lung injury (ALI) and investigate its potential pathogenesis. An LPS-induced ALI model was produced with LPS (5 mg/kg) followed by 24 h of inju...

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Hoofdauteurs: Bin Wang, Jiaoyue Wang, Daopeng Lu, Na Qi, Qin Liu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis Group 2021-03-01
Reeks:Journal of Investigative Surgery
Onderwerpen:
acute lung injury
lipopolysaccharide
lyrm03
nf-κb
nlrp3 inflammasome
tlr4
Online toegang:http://dx.doi.org/10.1080/08941939.2019.1634165
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