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Pituitary-Specific Knockout of the Carney Complex Gene Prkar1a Leads to Pituitary Tumorigenesis

Carney complex (CNC) is an inherited neoplasia syndrome characterized by spotty skin pigmentation, myxomas, endocrine tumors, and schwannomas. Among the endocrine tumors that comprise the syndrome, GH-producing pituitary tumors are seen in approximately 10% of patients, although biochemical abnormal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yin, Zhirong, Williams-Simons, Lisa, Parlow, A. F., Asa, Sylvia, Kirschner, Lawrence S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Endocrine Society 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234591/
https://ncbi.nlm.nih.gov/pubmed/17975024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2006-0428
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