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Pituitary-Specific Knockout of the Carney Complex Gene Prkar1a Leads to Pituitary Tumorigenesis

Carney complex (CNC) is an inherited neoplasia syndrome characterized by spotty skin pigmentation, myxomas, endocrine tumors, and schwannomas. Among the endocrine tumors that comprise the syndrome, GH-producing pituitary tumors are seen in approximately 10% of patients, although biochemical abnormal...

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Hlavní autoři: Yin, Zhirong, Williams-Simons, Lisa, Parlow, A. F., Asa, Sylvia, Kirschner, Lawrence S.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234591/
https://ncbi.nlm.nih.gov/pubmed/17975024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2006-0428
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