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Vascular Endothelial Growth Factor Receptor-2 Expression Is Down-Regulated by 17β-Estradiol in MCF-7 Breast Cancer Cells by Estrogen Receptor α/Sp Proteins
17β-Estradiol (E2) induces and represses gene expression in breast cancer cells; however, the mechanisms of gene repression are not well understood. In this study, we show that E2 decreases vascular endothelial growth factor receptor 2 (VEGFR2) mRNA levels in MCF-7 cells, and this gene was used as a...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Endocrine Society
2008
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234589/ https://ncbi.nlm.nih.gov/pubmed/18006642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0319 |
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