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MECHANISM OF PROFLAVIN MUTAGENESIS

The mutagenic action of proflavin on bacteriophage T4 is greater in the presence of defective T4 ligase than in the presence of normal T4 ligase. This suggests that the persistence of single-strand breaks in DNA enhances proflavin mutagenesis.

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Sarabhai, Anand, Lamfrom, Hildegard
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1969
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC223449/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5260919/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.63.4.1196
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