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Suppression of Chemical Mutagenesis in Bacteriophage T4 by Genetically Modified DNA Polymerases

Two antimutagenic DNA polymerases of bacteriophage T4 markedly reduce transition mutagenesis by a variety of chemical mutagens. Spontaneous mutation and mutagenesis by 2-aminopurine, 5-bromodeoxyuridine, and thymine deprivation are strongly suppressed. Mutagenesis at G:C sites by ethyl methanesulfon...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Drake, John W., Greening, Elaine O.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1970
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283124/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5269245/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.66.3.823
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