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MECHANISM OF PROFLAVIN MUTAGENESIS

The mutagenic action of proflavin on bacteriophage T4 is greater in the presence of defective T4 ligase than in the presence of normal T4 ligase. This suggests that the persistence of single-strand breaks in DNA enhances proflavin mutagenesis.

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sarabhai, Anand, Lamfrom, Hildegard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1969
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC223449/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5260919/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.63.4.1196
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