Characterization of anticoagulant heparinoids by immunoprofiling

Heparinoids are used in the clinic as anticoagulants. A specific pentasaccharide in heparinoids activates antithrombin III, resulting in inactivation of factor Xa and–when additional saccharides are present–inactivation of factor IIa. Structural and functional analysis of the heterogeneous heparinoi...

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Detalhes bibliográficos
Main Authors: Wijnhoven, Tessa J., van de Westerlo, Els M., Smits, Nicole C., Lensen, Joost F., Rops, Angelique L., van der Vlag, Johan, Berden, Jo H., van den Heuvel, Lambert P., van Kuppevelt, Toin H.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234449/
https://ncbi.nlm.nih.gov/pubmed/17909966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-007-9070-z
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