Characterization of anticoagulant heparinoids by immunoprofiling

Heparinoids are used in the clinic as anticoagulants. A specific pentasaccharide in heparinoids activates antithrombin III, resulting in inactivation of factor Xa and–when additional saccharides are present–inactivation of factor IIa. Structural and functional analysis of the heterogeneous heparinoi...

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Autors principals: Wijnhoven, Tessa J., van de Westerlo, Els M., Smits, Nicole C., Lensen, Joost F., Rops, Angelique L., van der Vlag, Johan, Berden, Jo H., van den Heuvel, Lambert P., van Kuppevelt, Toin H.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234449/
https://ncbi.nlm.nih.gov/pubmed/17909966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-007-9070-z
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