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Cripto promotes A–P axis specification independently of its stimulatory effect on Nodal autoinduction
The EGF-CFC gene cripto governs anterior–posterior (A–P) axis specification in the vertebrate embryo. Existing models suggest that Cripto facilitates binding of Nodal to an ActRII–activin-like kinase (ALK) 4 receptor complex. Cripto also has a crucial function in cellular transformation that is inde...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234230/ https://ncbi.nlm.nih.gov/pubmed/18268105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200709090 |
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