The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development

Nodal proteins have crucial roles in mesendoderm formation and left–right patterning during vertebrate development. The molecular mechanisms of signal transduction by Nodal and related ligands, however, are not fully understood. In this paper, we present biochemical and functional evidence that the...

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Detalhes bibliográficos
Main Authors: Reissmann, Eva, Jörnvall, Henrik, Blokzijl, Andries, Andersson, Olov, Chang, Chenbei, Minchiotti, Gabriella, Persico, M. Graziella, Ibáñez, Carlos F., Brivanlou, Ali H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312747/
https://ncbi.nlm.nih.gov/pubmed/11485994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.201801
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