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Mast cell renin and a local renin–angiotensin system in the airway: Role in bronchoconstriction

We previously reported that mast cells express renin, the rate-limiting enzyme in the renin–angiotensin cascade. We have now assessed whether mast cell renin release triggers angiotensin formation in the airway. In isolated rat bronchial rings, mast cell degranulation released enzyme with angiotensi...

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Detalhes bibliográficos
Main Authors: Veerappan, Arul, Reid, Alicia C., Estephan, Racha, O'Connor, Nathan, Thadani-Mulero, Maria, Salazar-Rodriguez, Mariselis, Levi, Roberto, Silver, Randi B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234135/
https://ncbi.nlm.nih.gov/pubmed/18202178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709739105
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