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Mast cells are required for the development of renal fibrosis in the rodent unilateral ureteral obstruction model

Mast cells are associated with inflammation and fibrosis. Whether they protect against or contribute to renal fibrosis is unclear. Based on our previous findings that mast cells can express and secrete active renin, and that angiotensin (ANG II) is profibrotic, we hypothesized that mast cells play a...

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Detalhes bibliográficos
Main Authors: Veerappan, Arul, Reid, Alicia C., O'Connor, Nathan, Mora, Rosalia, Brazin, Jacqueline A., Estephan, Racha, Kameue, Takashi, Chen, Jie, Felsen, Diane, Seshan, Surya V., Poppas, Dix P., Maack, Thomas, Silver, Randi B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251335/
https://ncbi.nlm.nih.gov/pubmed/21957176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00562.2010
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