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Mast cells are required for the development of renal fibrosis in the rodent unilateral ureteral obstruction model
Mast cells are associated with inflammation and fibrosis. Whether they protect against or contribute to renal fibrosis is unclear. Based on our previous findings that mast cells can express and secrete active renin, and that angiotensin (ANG II) is profibrotic, we hypothesized that mast cells play a...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251335/ https://ncbi.nlm.nih.gov/pubmed/21957176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00562.2010 |
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