Mast cells are required for the development of renal fibrosis in the rodent unilateral ureteral obstruction model

Mast cells are associated with inflammation and fibrosis. Whether they protect against or contribute to renal fibrosis is unclear. Based on our previous findings that mast cells can express and secrete active renin, and that angiotensin (ANG II) is profibrotic, we hypothesized that mast cells play a...

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Hauptverfasser: Veerappan, Arul, Reid, Alicia C., O'Connor, Nathan, Mora, Rosalia, Brazin, Jacqueline A., Estephan, Racha, Kameue, Takashi, Chen, Jie, Felsen, Diane, Seshan, Surya V., Poppas, Dix P., Maack, Thomas, Silver, Randi B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251335/
https://ncbi.nlm.nih.gov/pubmed/21957176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00562.2010
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