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Mast cell renin and a local renin–angiotensin system in the airway: Role in bronchoconstriction

We previously reported that mast cells express renin, the rate-limiting enzyme in the renin–angiotensin cascade. We have now assessed whether mast cell renin release triggers angiotensin formation in the airway. In isolated rat bronchial rings, mast cell degranulation released enzyme with angiotensi...

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Autors principals: Veerappan, Arul, Reid, Alicia C., Estephan, Racha, O'Connor, Nathan, Thadani-Mulero, Maria, Salazar-Rodriguez, Mariselis, Levi, Roberto, Silver, Randi B.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234135/
https://ncbi.nlm.nih.gov/pubmed/18202178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709739105
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