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B-cell receptor activation inhibits AID expression through calmodulin inhibition of E-proteins
Upon encountering antigens, B-lymphocytes can adapt to produce a highly specific and potent antibody response. Somatic hypermutation, which introduces point mutations in the variable regions of antibody genes, can increase the affinity for antigen, and antibody effector functions can be altered by c...
Tallennettuna:
| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234127/ https://ncbi.nlm.nih.gov/pubmed/18203819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708220105 |
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