Ca(2+)-independent inhibition of inositol trisphosphate receptors by calmodulin: Redistribution of calmodulin as a possible means of regulating Ca(2+) mobilization

The interactions between calmodulin, inositol 1,4,5-trisphosphate (InsP(3)), and pure cerebellar InsP(3) receptors were characterized by using a scintillation proximity assay. In the absence of Ca(2+), (125)I-labeled calmodulin reversibly bound to multiple sites on InsP(3) receptors and Ca(2+) incre...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Patel, Sandip, Morris, Stephen A., Adkins, Charles E., O’Beirne, Gerry, Taylor, Colin W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23558/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326661/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11627
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