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Regulation of Escherichia coli SOS mutagenesis by dimeric intrinsically disordered umuD gene products

Products of the umuD gene in Escherichia coli play key roles in coordinating the switch from accurate DNA repair to mutagenic translesion DNA synthesis (TLS) during the SOS response to DNA damage. Homodimeric UmuD(2) is up-regulated 10-fold immediately after damage, after which slow autocleavage rem...

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Bibliografski detalji
Glavni autori: Simon, S. M., Sousa, F. J. R., Mohana-Borges, R., Walker, G. C.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234107/
https://ncbi.nlm.nih.gov/pubmed/18216271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706067105
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