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Regulation of Escherichia coli SOS mutagenesis by dimeric intrinsically disordered umuD gene products
Products of the umuD gene in Escherichia coli play key roles in coordinating the switch from accurate DNA repair to mutagenic translesion DNA synthesis (TLS) during the SOS response to DNA damage. Homodimeric UmuD(2) is up-regulated 10-fold immediately after damage, after which slow autocleavage rem...
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| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234107/ https://ncbi.nlm.nih.gov/pubmed/18216271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706067105 |
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