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The Dimeric SOS Mutagenesis Protein UmuD Is Active as a Monomer

The homodimeric umuD gene products play key roles in regulating the cellular response to DNA damage in Escherichia coli. UmuD(2) is composed of 139-amino acid subunits and is up-regulated as part of the SOS response. Subsequently, damage-induced RecA·ssDNA nucleoprotein filaments mediate the slow se...

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Bibliographic Details
Main Authors: Ollivierre, Jaylene N., Sikora, Jacquelyn L., Beuning, Penny J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030365/
https://ncbi.nlm.nih.gov/pubmed/21118802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.167254
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