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Globin switches in yolk sac–like primitive and fetal-like definitive red blood cells produced from human embryonic stem cells

We have previously shown that coculture of human embryonic stem cells (hESCs) for 14 days with immortalized fetal hepatocytes yields CD34(+) cells that can be expanded in serum-free liquid culture into large numbers of megaloblastic nucleated erythroblasts resembling yolk sac–derived cells. We show...

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Main Authors: Qiu, Caihong, Olivier, Emmanuel N., Velho, Michelle, Bouhassira, Eric E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234066/
https://ncbi.nlm.nih.gov/pubmed/18024790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-102087
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