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Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia
Decitabine's mechanism of action in chronic myelomonocytic leukemia remains incompletely understood. We studied the dynamics of neoplastic cell clearance during decitabine treatment (100 mg/m(2) per course every 4 weeks) using quantitative monitoring of mutant alleles by pyrosequencing. Patient...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234065/ https://ncbi.nlm.nih.gov/pubmed/18055864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-103960 |
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