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Gating Charges in the Activation and Inactivation Processes of the hERG Channel

The hERG channel has a relatively slow activation process but an extremely fast and voltage-sensitive inactivation process. Direct measurement of hERG's gating current (Piper, D.R., A. Varghese, M.C. Sanguinetti, and M. Tristani-Firouzi. 2003. PNAS. 100:10534–10539) reveals two kinetic componen...

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Bibliographic Details
Main Authors: Zhang, Mei, Liu, Jie, Tseng, Gea-Ny
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234031/
https://ncbi.nlm.nih.gov/pubmed/15545400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409119
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