Laddar...
Block of Inactivation-deficient Na(+) Channels by Local Anesthetics in Stably Transfected Mammalian Cells: Evidence for Drug Binding Along the Activation Pathway
According to the classic modulated receptor hypothesis, local anesthetics (LAs) such as benzocaine and lidocaine bind preferentially to fast-inactivated Na(+) channels with higher affinities. However, an alternative view suggests that activation of Na(+) channels plays a crucial role in promoting hi...
Sparad:
| Huvudupphovsmän: | , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The Rockefeller University Press
2004
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234030/ https://ncbi.nlm.nih.gov/pubmed/15545401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409128 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|