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Luminal Ca(2+)–regulated Mg(2+) Inhibition of Skeletal RyRs Reconstituted as Isolated Channels or Coupled Clusters
In resting muscle, cytoplasmic Mg(2+) is a potent inhibitor of Ca(2+) release from the sarcoplasmic reticulum (SR). It is thought to inhibit calcium release channels (RyRs) by binding both to low affinity, low specificity sites (I-sites) and to high affinity Ca(2+) sites (A-sites) thus preventing Ca...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Rockefeller University Press
2004
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234024/ https://ncbi.nlm.nih.gov/pubmed/15545399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409092 |
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