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Luminal Mg(2+), A Key Factor Controlling RYR2-mediated Ca(2+) Release: Cytoplasmic and Luminal Regulation Modeled in a Tetrameric Channel
In cardiac muscle, intracellular Ca(2+) and Mg(2+) are potent regulators of calcium release from the sarcoplasmic reticulum (SR). It is well known that the free [Ca(2+)] in the SR ([Ca(2+)](L)) stimulates the Ca(2+) release channels (ryanodine receptor [RYR]2). However, little is known about the act...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2553390/ https://ncbi.nlm.nih.gov/pubmed/18824590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810001 |
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