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New Insights on the Voltage Dependence of the K(Ca)3.1 Channel Block by Internal TBA

We present in this work a structural model of the open IKCa (K(Ca)3.1) channel derived by homology modeling from the MthK channel structure, and used this model to compute the transmembrane potential profile along the channel pore. This analysis showed that the selectivity filter and the region exte...

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Autori principali: Banderali, Umberto, Klein, Hélène, Garneau, Line, Simoes, Manuel, Parent, Lucie, Sauvé, Rémy
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233899/
https://ncbi.nlm.nih.gov/pubmed/15452196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409145
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