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New Insights on the Voltage Dependence of the K(Ca)3.1 Channel Block by Internal TBA

We present in this work a structural model of the open IKCa (K(Ca)3.1) channel derived by homology modeling from the MthK channel structure, and used this model to compute the transmembrane potential profile along the channel pore. This analysis showed that the selectivity filter and the region exte...

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Detalhes bibliográficos
Main Authors: Banderali, Umberto, Klein, Hélène, Garneau, Line, Simoes, Manuel, Parent, Lucie, Sauvé, Rémy
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233899/
https://ncbi.nlm.nih.gov/pubmed/15452196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409145
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