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Contribution of the KCa3.1 channel–calmodulin interactions to the regulation of the KCa3.1 gating process

The Ca(2+)-activated potassium channel of intermediate conductance, KCa3.1, is now emerging as a therapeutic target for a large variety of health disorders. The Ca(2+) sensitivity of KCa3.1 is conferred by the Ca(2+)-binding protein calmodulin (CaM), with the CaM C-lobe constitutively bound to an in...

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Hlavní autoři: Morales, Patricia, Garneau, Line, Klein, Hélène, Lavoie, Marie-France, Parent, Lucie, Sauvé, Rémy
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691446/
https://ncbi.nlm.nih.gov/pubmed/23797421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210933
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