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Voltage-Controlled Gating at the Intracellular Entrance to a Hyperpolarization-Activated Cation Channel
Hyperpolarization-activated cation (HCN) channels regulate pacemaking activity in cardiac cells and neurons. Our previous work using the specific HCN channel blocker ZD7288 provided evidence for an intracellular activation gate for these channels because it appears that ZD7288, applied from the intr...
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Auteurs principaux: | , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
The Rockefeller University Press
2002
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2233860/ https://ncbi.nlm.nih.gov/pubmed/11773240 |
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