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Voltage-Controlled Gating at the Intracellular Entrance to a Hyperpolarization-Activated Cation Channel

Hyperpolarization-activated cation (HCN) channels regulate pacemaking activity in cardiac cells and neurons. Our previous work using the specific HCN channel blocker ZD7288 provided evidence for an intracellular activation gate for these channels because it appears that ZD7288, applied from the intr...

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書目詳細資料
Main Authors: Rothberg, Brad S., Shin, Ki Soon, Phale, Prashant S., Yellen, Gary
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233860/
https://ncbi.nlm.nih.gov/pubmed/11773240
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