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Allosteric Regulation of Bk Channel Gating by Ca(2+) and Mg(2+) through a Nonselective, Low Affinity Divalent Cation Site

The ability of membrane voltage to activate high conductance, calcium-activated (BK-type) K(+) channels is enhanced by cytosolic calcium (Ca(2+)). Activation is sensitive to a range of [Ca(2+)] that spans over four orders of magnitude. Here, we examine the activation of BK channels resulting from ex...

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Detalhes bibliográficos
Main Authors: Zhang, X., Solaro, C.R., Lingle, C.J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233841/
https://ncbi.nlm.nih.gov/pubmed/11696615
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