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Elimination of the BK(Ca) Channel's High-Affinity Ca(2+) Sensitivity
We report here a combination of site-directed mutations that eliminate the high-affinity Ca(2+) response of the large-conductance Ca(2+)-activated K(+) channel (BK(Ca)), leaving only a low-affinity response blocked by high concentrations of Mg(2+). Mutations at two sites are required, the “Ca(2+) bo...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234461/ https://ncbi.nlm.nih.gov/pubmed/12149279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20028627 |
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