Activating Effect of Benzbromarone, a Uricosuric Drug, on Peroxisome Proliferator-Activated Receptors

Benzbromarone, a uricosuric drug, reportedly causes hepatic hypertrophy accompanied by proliferation of peroxisomes in rats. To elucidate the mechanisms underlying induction of peroxisome proliferation by benzbromarone, we examined binding affinity for peroxisome proliferator-activated receptor [For...

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Библиографические подробности
Главные авторы: Kunishima, Chiyoko, Inoue, Ikuo, Oikawa, Toshihiro, Nakajima, Hiromu, Komoda, Tsugikazu, Katayama, Shigehiro
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2007
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233808/
https://ncbi.nlm.nih.gov/pubmed/18274627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2007/36092
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