Activating Effect of Benzbromarone, a Uricosuric Drug, on Peroxisome Proliferator-Activated Receptors

Benzbromarone, a uricosuric drug, reportedly causes hepatic hypertrophy accompanied by proliferation of peroxisomes in rats. To elucidate the mechanisms underlying induction of peroxisome proliferation by benzbromarone, we examined binding affinity for peroxisome proliferator-activated receptor [For...

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Bibliographic Details
Main Authors: Kunishima, Chiyoko, Inoue, Ikuo, Oikawa, Toshihiro, Nakajima, Hiromu, Komoda, Tsugikazu, Katayama, Shigehiro
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2007
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233808/
https://ncbi.nlm.nih.gov/pubmed/18274627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2007/36092
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