Activating Effect of Benzbromarone, a Uricosuric Drug, on Peroxisome Proliferator-Activated Receptors

Benzbromarone, a uricosuric drug, reportedly causes hepatic hypertrophy accompanied by proliferation of peroxisomes in rats. To elucidate the mechanisms underlying induction of peroxisome proliferation by benzbromarone, we examined binding affinity for peroxisome proliferator-activated receptor [For...

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Detalhes bibliográficos
Main Authors: Kunishima, Chiyoko, Inoue, Ikuo, Oikawa, Toshihiro, Nakajima, Hiromu, Komoda, Tsugikazu, Katayama, Shigehiro
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233808/
https://ncbi.nlm.nih.gov/pubmed/18274627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2007/36092
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