Activating Effect of Benzbromarone, a Uricosuric Drug, on Peroxisome Proliferator-Activated Receptors

Benzbromarone, a uricosuric drug, reportedly causes hepatic hypertrophy accompanied by proliferation of peroxisomes in rats. To elucidate the mechanisms underlying induction of peroxisome proliferation by benzbromarone, we examined binding affinity for peroxisome proliferator-activated receptor [For...

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Autors principals: Kunishima, Chiyoko, Inoue, Ikuo, Oikawa, Toshihiro, Nakajima, Hiromu, Komoda, Tsugikazu, Katayama, Shigehiro
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233808/
https://ncbi.nlm.nih.gov/pubmed/18274627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2007/36092
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