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S4 Charges Move Close to Residues in the Pore Domain during Activation in a K Channel

Voltage-gated ion channels respond to changes in the transmembrane voltage by opening or closing their ion conducting pore. The positively charged fourth transmembrane segment (S4) has been identified as the main voltage sensor, but the mechanisms of coupling between the voltage sensor and the gates...

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Detalhes bibliográficos
Main Authors: Elinder, Fredrik, Männikkö, Roope, Larsson, H. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233763/
https://ncbi.nlm.nih.gov/pubmed/11429439
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