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Molecular Basis of Ca(2)+ Activation of the Mouse Cardiac Ca(2)+ Release Channel (Ryanodine Receptor)

Activation of the cardiac ryanodine receptor (RyR2) by Ca(2)+ is an essential step in excitation-contraction coupling in heart muscle. However, little is known about the molecular basis of activation of RyR2 by Ca(2)+. In this study, we investigated the role in Ca(2)+ sensing of the conserved glutam...

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Detalhes bibliográficos
Main Authors: Li, Pin, Chen, S.R. Wayne
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233748/
https://ncbi.nlm.nih.gov/pubmed/11429443
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