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Mutations within the P-Loop of Kir6.2 Modulate the Intraburst Kinetics of the Atp-Sensitive Potassium Channel

The ATP-sensitive potassium (K(ATP)) channel exhibits spontaneous bursts of rapid openings, which are separated by long closed intervals. Previous studies have shown that mutations at the internal mouth of the pore-forming (Kir6.2) subunit of this channel affect the burst duration and the long inter...

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Autori principali: Proks, Peter, Capener, Charlotte E., Jones, Phillippa, Ashcroft, Frances M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233698/
https://ncbi.nlm.nih.gov/pubmed/11585848
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