Probing cell-surface architecture through synthesis: An NMR-determined structural motif for tumor-associated mucins

Cell-surface mucin glycoproteins are altered with the onset of oncogenesis. Knowledge of mucin structure could be used in vaccine strategies that target tumor-associated mucin motifs. Thus far, however, mucins have resisted detailed molecular analysis. Reported herein is the solution conformation of...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Live, David H., Williams, Lawrence J., Kuduk, Scott D., Schwarz, Jacob B., Glunz, Peter W., Chen, Xiao-Tao, Sames, Dalibor, Kumar, R. Ajay, Danishefsky, Samuel J.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1999
Sujets:	Physical Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22319/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10097062/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.7.3489
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