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Cell systems and the toxic mechanism(s) of α-synuclein

Mutations in the SNCA gene are causal for familial Parkinson disease/Lewy body disease. α-Synuclein is a small acidic protein that binds loosely to the surface of vesicles and may play a role in synaptic dynamics, although its normal function remains somewhat unclear. What is clear is that point mut...

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Détails bibliographiques
Auteurs principaux: Cookson, Mark R, van der Brug, Marcel
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2231843/
https://ncbi.nlm.nih.gov/pubmed/17603039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2007.05.022
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