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Pore mutations alter closing and opening kinetics in Shaker K(+) channels

1. We have studied the effects of mutations of amino acids in the pore (positions 447 and 449) and the elevation of extracellular [K(+)] on the closing and opening kinetics of Shaker B K(+) channels transiently expressed in Chinese hamster ovary (CHO) cells. 2. Mutant D447E had closing and C-type in...

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Bibliografske podrobnosti
Main Authors: Molina, A, Ortega-Sáenz, P, López-Barneo, J
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230968/
https://ncbi.nlm.nih.gov/pubmed/9575283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.327bn.x
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