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S4 mutations alter gating currents of Shaker K channels.

Activation of voltage-dependent channels involves charge-moving conformational changes of the voltage sensor that can be detected as gating currents. In Shaker K channels, the S4 sequence comprises at least part of the voltage sensor. We have measured gating currents in three S4 mutants: R368Q, R377...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Perozo, E, Santacruz-Toloza, L, Stefani, E, Bezanilla, F, Papazian, D M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1994
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1275701/
https://ncbi.nlm.nih.gov/pubmed/8161688
Tagiau: Ychwanegu Tag
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