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A single nucleotide mutation in the mouse renin promoter disrupts blood pressure regulation
Renin, a major regulatory component of the renin-angiotensin system, plays a pivotal role in regulating blood pressure and electrolyte homeostasis and is predominantly expressed in the kidney. Several cAMP-responsive elements have been identified within renin gene promoters. Here, we study how 2 suc...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2230662/ https://ncbi.nlm.nih.gov/pubmed/18259612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33824 |
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